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\u4f5c\u70ba\u570b\u5167\u9996\u500b\u665a\u671f\u814e\u764c\u514d\u75ab\u6cbb\u7642\u95dc\u9375III\u671f\u7814\u7a76\uff0cRENOTORCH\u7814\u7a76\uff08NCT04394975\uff09\u662f\u4e00\u9805\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u958b\u653e\u3001\u967d\u6027\u85e5\u5c0d\u7167\u7684III\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8a55\u4f30\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u963f\u6614\u66ff\u5c3c\u5c0d\u6bd4\u8212\u5c3c\u66ff\u5c3c\u4e00\u7dda\u6cbb\u7642\u4e2d\u9ad8\u5371\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f49\u79fb\u6027RCC\u60a3\u8005\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u3002\u6839\u64da\u672c\u7814\u7a76\u7684\u671f\u4e2d\u5206\u6790\u7d50\u679c\uff0c\u76f8\u8f03\u4e8e\u8212\u5c3c\u66ff\u5c3c\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u963f\u6614\u66ff\u5c3c\u4e00\u7dda\u6cbb\u7642\u665a\u671fRCC\u60a3\u8005\u53ef\u986f\u8457\u964d\u4f4e\u60a3\u8005\u7684\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\uff0c\u540c\u6642\u6539\u5584ORR\u7b49\u6b21\u8981\u7d42\u9ede\u3002\u7279\u745e\u666e\u5229\u55ae\u6297\u5b89\u5168\u6027\u8cc7\u6599\u8207\u5df2\u77e5\u98a8\u96aa\u76f8\u7b26\uff0c\u672a\u767c\u73fe\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u865f\u3002\u95dc\u65bc\u8a73\u7d30\u7684\u7814\u7a76\u8cc7\u6599\uff0c\u541b\u5be6\u751f\u7269\u5c07\u5728\u8fd1\u671f\u570b\u969b\u5b78\u8853\u5927\u6703\u4e0a\u516c\u4f48\u3002<\/p>\n\n\n\n

\u541b\u5be6\u751f\u7269\u5168\u7403\u7814\u767c\u7e3d\u88c1\u9112\u5efa\u8ecd\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u201c\u5728\u7814\u7a76\u8005\u3001\u60a3\u8005\u3001\u7814\u767c\u5718\u968a\u7b49\u5404\u65b9\u7684\u5171\u540c\u52aa\u529b\u4e0b\uff0cRENOTORCH\u7814\u7a76\u53d6\u5f97\u4e86\u6210\u529f\uff0c\u662f\u6211\u5011\u4f5c\u70ba\u672c\u571f\u5275\u65b0\u85e5\u4f01\u2018\u7acb\u8db3\u4e2d\u570b\u2019\uff0c\u512a\u5148\u6eff\u8db3\u570b\u4eba\u672a\u76e1\u9700\u6c42\u7684\u91cd\u8981\u5be6\u8e10\uff0c\u6b64\u6b21\u9054\u6210\u967d\u6027\u7d50\u679c\u5c07\u6709\u671b\u586b\u88dc\u570b\u5167\u814e\u764cPD-(L)1\u514d\u75ab\u6cbb\u7642\u9818\u57df\u7684\u7a7a\u767d\u3002\u6211\u5011\u5c07\u7a4d\u6975\u63a8\u52d5\u9019\u9805\u6210\u679c\u7684\u5546\u696d\u5316\u843d\u5730\uff0c\u4ee5\u671f\u70ba\u570b\u5167\u60a3\u8005\u63d0\u4f9b\u65b0\u578b\u3001\u6709\u6548\u7684\u514d\u75ab\u806f\u5408\u6cbb\u7642\u65b0\u9078\u64c7\uff01\u201c<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n
1.\u00a0\u00a0\u00a0\u00a0 \u4e2d\u83ef\u4eba\u6c11\u5171\u548c\u570b\u570b\u5bb6\u885b\u751f\u5065\u5eb7\u59d4\u54e1\u6703. \u300a\u814e\u7d30\u80de\u764c\u8a3a\u7642\u6307\u5357\uff082022\u5e74\u7248\uff09\u300b. 2022.<\/h5>\n\n\n\n
2.     Xia C, Dong X, Li H, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants. Chin Med J (Engl) 2022;135:584-90.<\/h5>\n\n\n\n
3.     Padala SA, Barsouk A, Thandra KC, et al. Epidemiology of Renal Cell Carcinoma. World J Oncol 2020;11:79-87.<\/h5>\n\n\n\n
4.     Janzen NK, Kim HL, Figlin RA, Belldegrun AS. Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol Clin North Am 2003;30:843-52.<\/h5>\n\n\n\n
5.     Heng DY, Xie W, Regan MM, et al. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 2009;27:5794-9.<\/h5>\n\n\n\n
6.     Xu W, Atkins MB, McDermott DF. Checkpoint inhibitor immunotherapy in kidney cancer. Nat Rev Urol 2020;17:137-50.<\/h5>\n\n\n\n
<\/p>\n\n\n\n
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1. \u672c\u6750\u6599\u65e8\u5728\u50b3\u905e\u524d\u6cbf\u8cc7\u8a0a\uff0c\u7121\u610f\u5411\u60a8\u505a\u4efb\u4f55\u7522\u54c1\u7684\u63a8\u5ee3\uff0c\u4e0d\u4f5c\u70ba\u81e8\u5e8a\u7528\u85e5\u6307\u5c0e\u3002<\/em><\/h6>\n\n\n\n
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\u95dc\u65bc<\/strong>RENOTORCH<\/strong>\u7814\u7a76<\/strong><\/strong><\/p>\n\n\n\n
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\u95dc\u65bc\u7279\u745e\u666e\u5229\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca<\/strong>^{\u00ae<\/sup><\/strong>\uff09<\/strong><\/strong><\/p>\n\n\n\n}
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1.\u00a0\u00a0\u00a0\u00a0 \u4e2d\u83ef\u4eba\u6c11\u5171\u548c\u570b\u570b\u5bb6\u885b\u751f\u5065\u5eb7\u59d4\u54e1\u6703. \u300a\u814e\u7d30\u80de\u764c\u8a3a\u7642\u6307\u5357\uff082022\u5e74\u7248\uff09\u300b. 2022.<\/h5>\n\n\n\n

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