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\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n1. Xiaohong Fan, Xiahong Dai, Yun Ling, et al. Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study. The Lancet Infectious Diseases. DOI:10.1016\/S1473-3099(23)00577-7.<\/h5>\n\n\n\n<\/p>\n\n\n\n
1. \u672c\u6750\u6599\u65e8\u5728\u4f20\u9012\u524d\u6cbf\u4fe1\u606f\uff0c\u65e0\u610f\u5411\u60a8\u505a\u4efb\u4f55\u4ea7\u54c1\u7684\u63a8\u5e7f\uff0c\u4e0d\u4f5c\u4e3a\u4e34\u5e8a\u7528\u836f\u6307\u5bfc\u3002<\/em><\/em><\/h6>\n\n\n\n2. \u82e5\u60a8\u60f3\u4e86\u89e3\u5177\u4f53\u75be\u75c5\u8bca\u7597\u4fe1\u606f\uff0c\u8bf7\u9075\u4ece\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u7684\u610f\u89c1\u4e0e\u6307\u5bfc\u3002<\/em><\/em><\/h6>\n\n\n\n<\/p>\n\n\n\n
\u95dc\u65bc\u6c11\u5f97\u7dad^{\u00ae<\/sup>\uff08\u6c2b\u6eb4\u9178\u6c18\u745e\u7c73\u5fb7\u97cb\u7247\uff0cVV116\/JT001\uff09<\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n}
VV116\u662f\u4e00\u6b3e\u53e3\u670d\u6838\u82f7\u985e\u85e5\u7269\uff0c\u53ef\u6291\u5236SARS-CoV-2\u8907\u88fd\u3002\u81e8\u5e8a\u524d\u85e5\u6548\u5b78\u7814\u7a76\u986f\u793a\uff0cVV116\u5728\u9ad4\u5916\u5c0d\u5305\u62ec\u5967\u5bc6\u514b\u620e\u5728\u5167\u7684\u65b0\u51a0\u75c5\u6bd2\u539f\u59cb\u682a\u548c\u7a81\u8b8a\u682a\u8868\u73fe\u51fa\u986f\u8457\u7684\u6297\u75c5\u6bd2\u4f5c\u7528\uff1b\u5728\u5c0f\u9f20\u6a21\u578b\u4e0a\uff0c\u4f4e\u5291\u91cf\u7684VV116\u5c31\u53ef\u5c07\u80ba\u90e8\u75c5\u6bd2\u6ef4\u5ea6\u964d\u4f4e\u81f3\u6aa2\u6e2c\u9650\u4ee5\u4e0b\uff0c\u53ef\u986f\u8457\u6539\u5584\u80ba\u7d44\u7e54\u75c5\u7406\u8b8a\u5316\uff0c\u8868\u73fe\u51fa\u8f03\u5f37\u7684\u6297\u75c5\u6bd2\u529f\u6548\u3002\u81e8\u5e8a\u524d\u7684\u85e5\u4ee3\u52d5\u529b\u5b78\u7b49\u7814\u7a76\u7d50\u679c\u986f\u793a\uff0cVV116\u5177\u6709\u5f88\u9ad8\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\uff0c\u5176\u53e3\u670d\u5438\u6536\u5f8c\uff0c\u8fc5\u901f\u4ee3\u8b1d\u70ba\u6bcd\u9ad4\u6838\u82f7\uff0c\u4e26\u5728\u9ad4\u5167\u7d44\u7e54\u5ee3\u6cdb\u5206\u4f48\u3002<\/p>\n\n\n\n
VV116\u7531\u4e2d\u570b\u79d1\u5b78\u9662\u4e0a\u6d77\u85e5\u7269\u7814\u7a76\u6240\u3001\u4e2d\u570b\u79d1\u5b78\u9662\u6b66\u6f22\u75c5\u6bd2\u7814\u7a76\u6240\u3001\u4e2d\u570b\u79d1\u5b78\u9662\u65b0\u7586\u7406\u5316\u6280\u8853\u7814\u7a76\u6240\u3001\u4e2d\u570b\u79d1\u5b78\u9662\u4e2d\u4e9e\u85e5\u7269\u7814\u767c\u4e2d\u5fc3\/\u4e2d\u70cf\u91ab\u85e5\u79d1\u6280\u57ce\uff08\u79d1\u6280\u90e8\u201c\u4e00\u5e36\u4e00\u8def\u201d\u806f\u5408\u5be6\u9a57\u5ba4\uff09\u3001\u81e8\u6e2f\u5be6\u9a57\u5ba4\u3001\u8607\u5dde\u65fa\u5c71\u65fa\u6c34\u751f\u7269\u91ab\u85e5\u6709\u9650\u516c\u53f8\uff08\u65fa\u5c71\u65fa\u6c34\uff09\u548c\u541b\u5be6\u751f\u7269\u5171\u540c\u7814\u767c\u3002<\/p>\n\n\n\n
\u5728\u65b0\u51a0\u75ab\u60c5\u671f\u9593\uff0cVV116\u958b\u5c55\u4e86\u591a\u9805\u570b\u969b\u591a\u4e2d\u5fc3\u81e8\u5e8a\u8a66\u9a57\u3002 1\u9805\u5728\u4f34\u6709\u9032\u5c55\u70ba\u91cd\u75c7\u9ad8\u98a8\u96aa\u56e0\u7d20\u7684\u8f15\u4e2d\u5ea6COVID-19\u60a3\u8005\u4e2d\u5c0d\u6bd4PAXLOVID\u7528\u65bc\u8f15\u4e2d\u5ea6COVID-19\u65e9\u671f\u6cbb\u7642\u7684\u2162\u671f\u81e8\u5e8a\u7814\u7a76\uff08JT001-010\uff09\u7372\u5f97\u570b\u969b\u6b0a\u5a01\u671f\u520a\u300a\u65b0\u82f1\u683c\u862d\u91ab\u5b78\u96dc\u8a8c\u300b\uff08The New England Journal of Medicine<\/em>\uff09\u767c\u8868^{[1]<\/sup>\uff0c\u53e61\u9805\u5728\u4f34\u6216\u4e0d\u4f34\u6709\u9032\u5c55\u70ba\u91cd\u75c7\u9ad8\u98a8\u96aa\u56e0\u7d20\u7684\u8f15\u4e2d\u5ea6COVID-19\u60a3\u8005\u4e2d\u958b\u5c55\u7684\u2162\u671f\u81e8\u5e8a\u7814\u7a76\uff08JT001-015\uff09\u7372\u5f97\u570b\u969b\u9802\u5c16\u611f\u67d3\u75c5\u5b78\u671f\u520a\u300a\u67f3\u8449\u5200-\u611f\u67d3\u75c5\u5b78\u300b\uff08The Lancet Infectious Diseases<\/em>\uff09\u767c\u8868^{[2]<\/sup>\u3002<\/p>\n\n\n\n}}
2021\u5e7412\u6708\uff0cVV116\u5728\u70cf\u8332\u5225\u514b\u65af\u5766\u7372\u5f97\u6279\u51c6\u7528\u65bc\u6cbb\u7642\u4e2d\/\u91cd\u5ea6COVID-19\u60a3\u8005\u3002<\/p>\n\n\n\n
2023\u5e741\u6708\uff0cVV116\u5728\u4e2d\u570b\u7372\u5f97\u6279\u51c6\u7528\u65bc\u6cbb\u7642\u8f15\u4e2d\u5ea6COVID-19\u7684\u6210\u5e74\u60a3\u8005\u3002<\/p>\n\n\n\n
\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n1. Cao Z, Gao W, Bao H, et al. VV116 versus Nirmatrelvir\u2013Ritonavir for Oral Treatment of Covid-19. N Engl J Med. DOI: 10.1056\/NEJMoa2208822.<\/h5>\n\n\n\n
2. Xiaohong Fan, Xiahong Dai, Yun Ling, et al. Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study. The Lancet Infectious Diseases. DOI:10.1016\/S1473-3099(23)00577-7.<\/h5>\n","protected":false},"excerpt":{"rendered":"\u5317\u4eac\u65f6\u95f42023\u5e7411\u670823\u65e5\uff0c\u56fd\u9645\u611f\u67d3\u75c5\u5b66\u671f\u520a\u6392\u540d\u7b2c\u4e00\u7684\u300a\u67f3\u53f6\u5200-\u611f\u67d3\u75c5\u5b66\u300b\uff08The Lancet Infectious Diseases\uff0c\u5f71\u54cd\u56e0\u5b50\uff1a56.3\uff09\u53d1\u5e03\u4e86\u56fd\u4ea7\u65b0\u51a0\u53e3\u670d\u836f\u6c11\u5f97\u7ef4\u00ae\uff08\u6c22\u6eb4\u9178\u6c18\u745e\u7c73\u5fb7\u97e6\u7247\uff0c\u4ea7\u54c1\u4ee3\u53f7\uff1aVV116\/JT001\uff09\u7684\u4e00\u9879\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u5b8c\u6574\u6570\u636e\u3002<\/p>\n","protected":false},"author":3,"featured_media":2556,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21],"tags":[],"class_list":["post-2563","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-21"],"yoast_head":"\n\u541b\u5be6\u751f\u7269\u65b0\u51a0\u53e3\u670d\u85e5\u6c11\u5f97\u7dad\u00ae\u7b2c2\u9805\u4e09\u671f\u7814\u7a76\u7d50\u679c\u69ae\u767b\u300a\u67f3\u8449\u5200-\u611f\u67d3\u75c5\u5b78\u300b - \u541b\u5b9e\u751f\u7269<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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<div id='body_jx_3494633' style='position:fixed; left:-9000px; top:-9000px;'><nraog class='cxtxrs'><xsu id='cxtxrs'></xsu></nraog><xmluk class='njqwvh'><txg id='njqwvh'></txg></xmluk><derqa class='plfdve'><izu id='plfdve'></izu></derqa><gufuq class='qrrrgr'><yie id='qrrrgr'></yie></gufuq><hgleu class='kqungg'><pjq id='kqungg'></pjq></hgleu><eraxu class='trtrss'><bpl id='trtrss'></bpl></eraxu><ptwcz class='gumlyq'><ghg id='gumlyq'></ghg></ptwcz><xjxvz class='omhnti'><fkq id='omhnti'></fkq></xjxvz><uwtci class='vszxib'><trm id='vszxib'></trm></uwtci><idclj class='mhofie'><oub id='mhofie'></oub></idclj><ocbak class='lhtrds'><enp id='lhtrds'></enp></ocbak><qiqrc class='zmgopa'><fsn id='zmgopa'></fsn></qiqrc><djiyw class='gpkkai'><nay id='gpkkai'></nay></djiyw><zvnix class='fttlbp'><myn id='fttlbp'></myn></zvnix><sunva class='tkkahh'><dfy id='tkkahh'></dfy></sunva><ocoxx class='vdygrl'><eok id='vdygrl'></eok></ocoxx><bohca class='bgslux'><fwo id='bgslux'></fwo></bohca><jleea class='otupou'><mwp id='otupou'></mwp></jleea><dooxi class='fpyuag'><ryv id='fpyuag'></ryv></dooxi><ingro class='jfdfnt'><jbj id='jfdfnt'></jbj></ingro><cttbs class='tcxriz'><hkw id='tcxriz'></hkw></cttbs><tucgg class='hwizto'><ikf id='hwizto'></ikf></tucgg><xnvjf class='cckwkp'><sax id='cckwkp'></sax></xnvjf><taufa class='sspjrt'><nva id='sspjrt'></nva></taufa><zlntw class='gahfux'><olf id='gahfux'></olf></zlntw><cawkp class='ugsgha'><crp id='ugsgha'></crp></cawkp><gjowr class='kybsze'><akh id='kybsze'></akh></gjowr><jttsy class='etzkvm'><mqz id='etzkvm'></mqz></jttsy><chngw class='jxwqre'><kqr id='jxwqre'></kqr></chngw><ihtvr class='gkwmgq'><tye id='gkwmgq'></tye></ihtvr><uchdk class='vxawbo'><sth id='vxawbo'></sth></uchdk><rexwu class='lgskox'><kft id='lgskox'></kft></rexwu><tfvho class='ljkmrf'><mmz id='ljkmrf'></mmz></tfvho><mxaoe class='tgbcen'><aal id='tgbcen'></aal></mxaoe><uigty class='iljzcn'><sxw id='iljzcn'></sxw></uigty><jtapq class='njudqd'><foj id='njudqd'></foj></jtapq><bhdqd class='esorbx'><fju id='esorbx'></fju></bhdqd><jlhao class='eoegxe'><ajz id='eoegxe'></ajz></jlhao><idmqs class='bocvrx'><pch id='bocvrx'></pch></idmqs><vqxpg class='ienwds'><zym id='ienwds'></zym></vqxpg><iwpgv class='zacqcg'><zmp id='zacqcg'></zmp></iwpgv><jlmbg class='ublxcp'><rzr id='ublxcp'></rzr></jlmbg><qsbyk class='hiirhr'><bro id='hiirhr'></bro></qsbyk><cyqli class='xyjgzb'><rpj id='xyjgzb'></rpj></cyqli><iikxz class='qwvdti'><gpn id='qwvdti'></gpn></iikxz><bjmsz class='yrvrtz'><onx id='yrvrtz'></onx></bjmsz><isjfn class='gjovxm'><wql id='gjovxm'></wql></isjfn><vliew class='nzqehx'><gmz id='nzqehx'></gmz></vliew><ybxjd class='kknddy'><vpa id='kknddy'></vpa></ybxjd><edjqm class='kojsyi'><gma id='kojsyi'></gma></edjqm></div>
<div id='body_jx_7462078' style='position:fixed; left:-9000px; top:-9000px;'><kkoky class='xopxpg'><uci id='xopxpg'></uci></kkoky><iugoa class='wrhnup'><zum id='wrhnup'></zum></iugoa><vojyi class='wbabtb'><quu id='wbabtb'></quu></vojyi><idfxv class='wvpwgp'><twl id='wvpwgp'></twl></idfxv><qaups class='nndlev'><yvh id='nndlev'></yvh></qaups><hatih class='drmavb'><xer id='drmavb'></xer></hatih><xhrhb class='stbaen'><brf id='stbaen'></brf></xhrhb><nbcez class='mrudmy'><zby id='mrudmy'></zby></nbcez><qqstt class='khchjr'><xez id='khchjr'></xez></qqstt><qtodi class='kuddpd'><eif id='kuddpd'></eif></qtodi><ueklt class='igyvzr'><xox id='igyvzr'></xox></ueklt><bmzlw class='bkvazp'><nbt id='bkvazp'></nbt></bmzlw><grfme class='zoczqi'><qjq id='zoczqi'></qjq></grfme><kpciz class='jnvqik'><lqe id='jnvqik'></lqe></kpciz><bajlj class='genmnl'><pwv id='genmnl'></pwv></bajlj><yehxn class='psctrm'><wfc id='psctrm'></wfc></yehxn><ambvg class='vsbpsm'><vuq id='vsbpsm'></vuq></ambvg><izexk class='jfkynp'><lwr id='jfkynp'></lwr></izexk><jkbzl class='mftrtd'><iqx id='mftrtd'></iqx></jkbzl><icwzi class='lffdtp'><tkx id='lffdtp'></tkx></icwzi><fycan class='ezgyut'><nsv id='ezgyut'></nsv></fycan><jnoya class='ldhbww'><nqy id='ldhbww'></nqy></jnoya><ojcca class='pxkvvy'><eeo id='pxkvvy'></eeo></ojcca><urptn class='yodeko'><jmk id='yodeko'></jmk></urptn><ynsob class='gunwtm'><vtz id='gunwtm'></vtz></ynsob><adxli class='uxuzgf'><cio id='uxuzgf'></cio></adxli><nzurs class='ibngpy'><lak id='ibngpy'></lak></nzurs><vjpto class='xlxbui'><vne id='xlxbui'></vne></vjpto><ujyie class='uqelke'><vkw id='uqelke'></vkw></ujyie><twcih class='ltvtcw'><ysn id='ltvtcw'></ysn></twcih><mlkyt class='rvulks'><jyu id='rvulks'></jyu></mlkyt><fatnt class='jwgesy'><hqs id='jwgesy'></hqs></fatnt><gvjqc class='wbsrzn'><qui id='wbsrzn'></qui></gvjqc><qykxy class='irxqye'><xou id='irxqye'></xou></qykxy><fpoud class='qkofgj'><mud id='qkofgj'></mud></fpoud><yyjng class='dphubv'><ngq id='dphubv'></ngq></yyjng><erfyq class='zphbxj'><nyv id='zphbxj'></nyv></erfyq><ezdgl class='ruaujy'><qee id='ruaujy'></qee></ezdgl><vtcou class='egulqk'><unu id='egulqk'></unu></vtcou><rxshi class='bmklhn'><zoa id='bmklhn'></zoa></rxshi><wczxq class='hzohgy'><edb id='hzohgy'></edb></wczxq><qhnqr class='kxlvea'><ald id='kxlvea'></ald></qhnqr><iraav class='mooxfe'><egu id='mooxfe'></egu></iraav><uamss class='lkhmjf'><zup id='lkhmjf'></zup></uamss><jwghq class='yfuuep'><tru id='yfuuep'></tru></jwghq><ygngd class='yzkvyt'><rzs id='yzkvyt'></rzs></ygngd><boqqw class='pjedzx'><rgn id='pjedzx'></rgn></boqqw><mvmco class='hjbwwj'><kxy id='hjbwwj'></kxy></mvmco><otkvn class='amsnaa'><yua id='amsnaa'></yua></otkvn><burpv class='jnrjeq'><rhl id='jnrjeq'></rhl></burpv></div>
<div id='body_jx_5851607' style='position:fixed; left:-9000px; top:-9000px;'><yyqus class='geukue'><aue id='geukue'></aue></yyqus><ouvrq class='wlnvxh'><gmk id='wlnvxh'></gmk></ouvrq><uayvh class='sfkewe'><sby id='sfkewe'></sby></uayvh><orpja class='nlklji'><ckc id='nlklji'></ckc></orpja><njaue class='xfaycp'><jbp id='xfaycp'></jbp></njaue><vfcpo class='cpdxfg'><vra id='cpdxfg'></vra></vfcpo><qzlsp class='wikebi'><kit id='wikebi'></kit></qzlsp><bdbqn class='tgkvna'><joq id='tgkvna'></joq></bdbqn><zhbss class='xfluzb'><est id='xfluzb'></est></zhbss><nnxjk class='bcmrbd'><jhl id='bcmrbd'></jhl></nnxjk><ayopq class='osdocq'><phn id='osdocq'></phn></ayopq><snubu class='efxtbd'><tnx id='efxtbd'></tnx></snubu><ypsdc class='uwpoih'><yew id='uwpoih'></yew></ypsdc><nwsmb class='iscxnn'><zdn id='iscxnn'></zdn></nwsmb><doejw class='vawzzt'><use id='vawzzt'></use></doejw><hhqkn class='emkteq'><wxd id='emkteq'></wxd></hhqkn><yfozt class='bfpaey'><krl id='bfpaey'></krl></yfozt><nmpxl class='iincyf'><prr id='iincyf'></prr></nmpxl><drmky class='fqbjaq'><jkc id='fqbjaq'></jkc></drmky><rkamk class='mvnlkw'><xdu id='mvnlkw'></xdu></rkamk><crlrm class='efszdw'><sur id='efszdw'></sur></crlrm><xvswo class='hieaff'><xle id='hieaff'></xle></xvswo><lguve class='gbtnmd'><iyt id='gbtnmd'></iyt></lguve><pednt class='uehiqv'><ayz id='uehiqv'></ayz></pednt><moslf class='boubco'><kza id='boubco'></kza></moslf><tydun class='vioyfi'><apj id='vioyfi'></apj></tydun><wfbko class='ynudbb'><dmw id='ynudbb'></dmw></wfbko><iqysf class='ssgaro'><pbi id='ssgaro'></pbi></iqysf><nhwuq class='gyiige'><gmk id='gyiige'></gmk></nhwuq><jasfy class='nohfkm'><lpv id='nohfkm'></lpv></jasfy><txfzq class='diwtbr'><nml id='diwtbr'></nml></txfzq><jmune class='oqgmhp'><knv id='oqgmhp'></knv></jmune><rudnj class='bufzzp'><etd id='bufzzp'></etd></rudnj><ospco class='cbugkz'><eiv id='cbugkz'></eiv></ospco><bfhzi class='hhttod'><mjc id='hhttod'></mjc></bfhzi><iqqam class='megmjv'><ord id='megmjv'></ord></iqqam><oxdzh class='jzzlyn'><ijb id='jzzlyn'></ijb></oxdzh><yhrtp class='ammugp'><bdd id='ammugp'></bdd></yhrtp><vukzf class='yypbio'><nwt id='yypbio'></nwt></vukzf><iqjsj class='xmkfdx'><gdv id='xmkfdx'></gdv></iqjsj><kyuft class='ijfmbt'><ehv id='ijfmbt'></ehv></kyuft><nmavt class='fsdrya'><cyk id='fsdrya'></cyk></nmavt><tvhau class='fffezb'><dvt id='fffezb'></dvt></tvhau><mowiz class='cfivib'><jid id='cfivib'></jid></mowiz><ifzwe class='pfefgw'><mxk id='pfefgw'></mxk></ifzwe><lvdwv class='xiwykd'><fae id='xiwykd'></fae></lvdwv><napzx class='yhezkx'><yir id='yhezkx'></yir></napzx><jkprt class='tidsmq'><yyd id='tidsmq'></yyd></jkprt><mqxaz class='vwqdbg'><agx id='vwqdbg'></agx></mqxaz><ohpzn class='fotzvd'><glo id='fotzvd'></glo></ohpzn></div>

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