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\u6b64\u524d\uff0cRENOTORCH\u7684\u7814\u7a76\u6210\u679c\u57282023\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08ESMO\uff09\u5927\u6703\u512a\u9078\u53e3\u982d\u5831\u544a\u5c08\u5834\u6703\u8b70\u4e0a\u9996\u6b21\u767c\u4f48\uff0c\u5168\u6587\u540c\u6b65\u7372ESMO\u5b98\u65b9\u671f\u520a\u300a\u816b\u7624\u5b78\u5e74\u9452\u300b\uff08Annals of Oncology<\/em>\uff1b\u5f71\u97ff\u56e0\u6578\uff1a50.5\uff1b\u816b\u7624\u9818\u57df\u5168\u7403\u6392\u540dTOP5\u7684\u9802\u7d1a\u671f\u520a\uff09\u767c\u8868\u3002\u7814\u7a76\u8cc7\u6599\u986f\u793a\uff0c\u57fa\u65bcIRC\u8a55\u4f30\u7d50\u679c\uff0c\u8207\u8212\u5c3c\u66ff\u5c3c\u55ae\u85e5\u6cbb\u7642\u76f8\u6bd4\uff0c\u63a5\u53d7\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u963f\u6614\u66ff\u5c3c\u6cbb\u7642\u53ef\u986f\u8457\u5ef6\u9577\u60a3\u8005\u7684PFS\uff08\u4e2d\u4f4dPFS\uff1a18.0 vs. 9.8\u500b\u6708\uff0cP=0.0028\uff09\uff0c\u60a3\u8005PFS\u5ef6\u9577\u8fd12\u500d\uff0c\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e35%\uff08\u98a8\u96aa\u6bd4[HR]=0.65\uff1b95%CI\uff1a0.49\uff0c0.86\uff09\u3002\u6b64\u5916\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u7d44\u7684ORR\u66f4\u512a\uff0856.7% vs. 30.8%\uff0cP<0.0001\uff09\uff0c\u4e26\u4e14DoR\u66f4\u9577\uff08\u4e2d\u4f4dDoR\uff1a\u672a\u9054\u5230 vs. 16.7\u500b\u6708\uff1bHR=0.61\uff09\uff0c\u5177\u6709\u660e\u986f\u7684OS\u7372\u76ca\u8da8\u52e2\uff08\u4e2d\u4f4dOS\uff1a\u672a\u9054\u5230 vs. 26.8\u500b\u6708\uff09\uff0c\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e39%\uff08HR=0.61\uff1b95%CI\uff1a0.40\uff0c0.92\uff09\u3002\u5b89\u5168\u6027\u65b9\u9762\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u963f\u6614\u66ff\u5c3c\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u767c\u73fe\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u865f\u3002<\/p>\n\n\n\n

\u5317\u4eac\u5927\u5b78\u816b\u7624\u91ab\u9662\u90ed\u8ecd\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201c\u5728\u5168\u7403\u5c64\u9762\uff0c\u9776\u5411\u806f\u5408\u514d\u75ab\u7642\u6cd5\u5df2\u6210\u70ba\u665a\u671f\u814e\u764c\u7684\u6a19\u6e96\u6cbb\u7642\uff0c\u4f46\u5728\u4e2d\u570b\u8a72\u9818\u57df\u5c1a\u7121\u76f8\u95dc\u7642\u6cd5\u7372\u6279\u3002\u6b64\u6b21\u7279\u745e\u666e\u5229\u55ae\u6297\u65b0\u9069\u61c9\u75c7\u7684\u7372\u6279\u958b\u555f\u4e86\u4e2d\u570b\u665a\u671f\u814e\u764c\u9776\u514d\u806f\u5408\u7684\u65b0\u7bc7\u7ae0\uff0c\u5c07\u6703\u5fb9\u5e95\u6539\u5beb\u6211\u570b\u665a\u671f\u814e\u764c\u7684\u81e8\u5e8a\u5be6\u8e10\uff0c\u66f4\u91cd\u8981\u7684\u662f\u80fd\u5920\u70ba\u4e2d\u9ad8\u5371\u60a3\u8005\u5e36\u4f86\u65b0\u7684\u6cbb\u7642\u9078\u64c7\uff01\u201d<\/p>\n\n\n\n

\u4e0a\u6d77\u4ea4\u901a\u5927\u5b78\u91ab\u5b78\u9662\u9644\u5c6c\u4ec1\u6fdf\u91ab\u9662\u9ec3\u7ffc\u7136\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201c\u665a\u671f\u814e\u764c\u7684\u6cbb\u7642\u624b\u6bb5\u6709\u9650\uff0c\u7279\u5225\u662f\u4e2d\u9ad8\u5371\u60a3\u8005\u7684\u9810\u5f8c\u5341\u5206\u4e0d\u7406\u60f3\u3002\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u963f\u6614\u66ff\u5c3c\u7642\u6cd5\u7684\u7372\u6279\u586b\u88dc\u4e86\u4e2d\u570b\u4eba\u7fa4\u814e\u764c\u4e00\u7dda\u514d\u75ab\u6cbb\u7642\u7684\u7a7a\u767d\uff0c\u76f8\u8f03\u9776\u5411\u85e5\u55ae\u85e5\u6cbb\u7642\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u9776\u514d\u806f\u5408\u7642\u6cd5\u80fd\u5920\u986f\u8457\u63d0\u5347\u60a3\u8005\u7684PFS\uff0c\u5c07\u70ba\u6211\u570b\u5ee3\u5927\u665a\u671f\u814e\u764c\u60a3\u8005\u5e36\u4f86\u798f\u97f3\u3002\u201d<\/p>\n\n\n\n

\u541b\u5be6\u751f\u7269\u7e3d\u7d93\u7406\u517c\u9996\u5e2d\u57f7\u884c\u5b98\u9112\u5efa\u8ecd\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u201c\u611f\u8b1d\u6240\u6709\u53c3\u8207RENOTORCH\u7814\u7a76\u7684\u91ab\u52d9\u5de5\u4f5c\u8005\u3001\u60a3\u8005\u4ee5\u53ca\u7814\u767c\u4eba\u54e1\u7684\u5949\u737b\uff0c\u8b93\u4e2d\u570b\u814e\u764c\u514d\u75ab\u6cbb\u7642\u5be6\u73fe\u2018\u96f6\u7684\u7a81\u7834\u2019\uff01\u541b\u5be6\u751f\u7269\u5c07\u7e7c\u7e8c\u7acb\u8db3\u65bc\u570b\u4eba\u7684\u81e8\u5e8a\u9700\u6c42\uff0c\u6301\u7e8c\u6295\u5165\u5275\u65b0\u7814\u767c\uff0c\u8b93\u4e2d\u570b\u60a3\u8005\u7372\u5f97\u66f4\u597d\u7684\u751f\u5b58\u54c1\u8cea\u548c\u66f4\u9577\u4e45\u7684\u751f\u5b58\u7372\u76ca\uff01\u201d<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n
1. \u4e2d\u83ef\u4eba\u6c11\u5171\u548c\u570b\u570b\u5bb6\u885b\u751f\u5065\u5eb7\u59d4\u54e1\u6703. \u300a\u814e\u7d30\u80de\u764c\u8a3a\u7642\u6307\u5357\uff082022\u5e74\u7248\uff09\u300b. 2022.<\/h5>\n\n\n\n
2. Xia C, Dong X, Li H, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants. Chin Med J (Engl) 2022;135:584-90.<\/h5>\n\n\n\n
3. Padala SA, Barsouk A, Thandra KC, et al. Epidemiology of Renal Cell Carcinoma. World J Oncol 2020;11:79-87.<\/h5>\n\n\n\n
4. Janzen NK, Kim HL, Figlin RA, Belldegrun AS. Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol Clin North Am 2003;30:843-52.<\/h5>\n\n\n\n
5. Heng DY, Xie W, Regan MM, et al. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 2009; 27:5794-9.<\/h5>\n\n\n\n
<\/p>\n\n\n\n
1. \u672c\u6750\u6599\u65e8\u5728\u50b3\u905e\u524d\u6cbf\u8cc7\u8a0a\uff0c\u7121\u610f\u5411\u60a8\u505a\u4efb\u4f55\u7522\u54c1\u7684\u63a8\u5ee3\uff0c\u4e0d\u4f5c\u70ba\u81e8\u5e8a\u7528\u85e5\u6307\u5c0e\u3002<\/em><\/em><\/h6>\n\n\n\n
2. \u82e5\u60a8\u60f3\u77ad\u89e3\u5177\u9ad4\u75be\u75c5\u8a3a\u7642\u8cc7\u8a0a\uff0c\u8acb\u9075\u5f9e\u91ab\u7642\u885b\u751f\u5c08\u696d\u4eba\u58eb\u7684\u610f\u898b\u8207\u6307\u5c0e\u3002<\/em><\/em><\/h6>\n","protected":false},"excerpt":{"rendered":"
\u7279\u745e\u666e\u5229\u55ae\u6297\u5728\u4e2d\u570b\u7372\u6279\u7b2c\u516b\u9805\u9069\u61c9\u75c7<\/p>\n","protected":false},"author":3,"featured_media":2761,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21],"tags":[],"class_list":["post-2789","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-21"],"yoast_head":"\n\u541b\u5be6\u751f\u7269\u5ba3\u4f48\u7279\u745e\u666e\u5229\u55ae\u6297\u814e\u764c\u9069\u61c9\u75c7\u5728\u4e2d\u570b\u7372\u6279 - \u541b\u5b9e\u751f\u7269<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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id='jlgolt'></sxk></vnkko><wccdw class='zwikrt'><rmn id='zwikrt'></rmn></wccdw><rofrn class='eplxhe'><syy id='eplxhe'></syy></rofrn><cdjus class='lvlimd'><ypr id='lvlimd'></ypr></cdjus><goeze class='ayfdrz'><yjn id='ayfdrz'></yjn></goeze><slxjj class='hqumqq'><vhn id='hqumqq'></vhn></slxjj><qwwpy class='sgyqlg'><map id='sgyqlg'></map></qwwpy><glmdm class='gvntbg'><ftp id='gvntbg'></ftp></glmdm><cjgul class='oywnhi'><vsa id='oywnhi'></vsa></cjgul><gbtlb class='gbiqpc'><xre id='gbiqpc'></xre></gbtlb><sarnp class='pezsjo'><imj id='pezsjo'></imj></sarnp><zkcrz class='qutktx'><sja id='qutktx'></sja></zkcrz><qxdhz class='miquih'><qlr id='miquih'></qlr></qxdhz><lpynz class='jiwokr'><pbl id='jiwokr'></pbl></lpynz><fzajw class='qoqazj'><ist id='qoqazj'></ist></fzajw><sbzvj class='ixwtzb'><tlx id='ixwtzb'></tlx></sbzvj><eymjx class='skufqm'><orr id='skufqm'></orr></eymjx><kmxjl class='iwlner'><dyj id='iwlner'></dyj></kmxjl><okubn class='jpjafd'><eii id='jpjafd'></eii></okubn><rotnq class='xyavbc'><yfc id='xyavbc'></yfc></rotnq><zfaiy class='kakudr'><dgd id='kakudr'></dgd></zfaiy><rcdan class='gjurzg'><rht id='gjurzg'></rht></rcdan><ibwec class='vhybvn'><mym id='vhybvn'></mym></ibwec><wurvf class='lzxcqx'><pbq id='lzxcqx'></pbq></wurvf><lbxlq class='jtjoyh'><mgd id='jtjoyh'></mgd></lbxlq><vxhio class='xolioj'><asf id='xolioj'></asf></vxhio><znkrj class='hohnbr'><cbn id='hohnbr'></cbn></znkrj><hbyti class='apugal'><znf id='apugal'></znf></hbyti><reuhf class='vrzrcy'><nwx id='vrzrcy'></nwx></reuhf><dgzls class='nmbazp'><han id='nmbazp'></han></dgzls><htbdo class='hfuysw'><isj id='hfuysw'></isj></htbdo><ywbvg class='nxqciv'><fdm id='nxqciv'></fdm></ywbvg><remqj class='vnedgb'><crm id='vnedgb'></crm></remqj><udaay class='lvaafn'><aqt id='lvaafn'></aqt></udaay><kyaje class='lulboe'><sih id='lulboe'></sih></kyaje><drtpg class='vcudct'><sqi id='vcudct'></sqi></drtpg></div> </body>

1. \u4e2d\u83ef\u4eba\u6c11\u5171\u548c\u570b\u570b\u5bb6\u885b\u751f\u5065\u5eb7\u59d4\u54e1\u6703. \u300a\u814e\u7d30\u80de\u764c\u8a3a\u7642\u6307\u5357\uff082022\u5e74\u7248\uff09\u300b. 2022.<\/h5>\n\n\n\n

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5. Heng DY, Xie W, Regan MM, et al. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 2009; 27:5794-9.<\/h5>\n\n\n\n
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